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Report all new or worsening symptoms to your doctor. Tell your doctor if you have ever had: bipolar disorder, a history of drug abuse, suicidal thoughts, glaucoma, seizures, epilepsy, low blood sodium, mental illness, Parkinson's disease, migraine headaches, severe infections. Bipolar disorder and mania should be checked before initiating treatment. Taking vortioxetine during the third trimester of pregnancy can cause withdrawal symptoms, lung problems, or other complications in the baby. Do not start or stop vortioxetine on your own without first consulting your doctor. Withdrawal symptoms may occur if you stop using vortioxetine suddenly. After stopping vortioxetine, wait at least 21 days before starting an MAO inhibitor. Avoid driving or doing dangerous activities as the side effects of vortioxetine can decrease your reaction. Tell your doctor if you are also taking stimulants, opioids, herbal products, or medications for depression. other antidepressants buspirone fentanyl, tramadol lithium St. John's wort, tryptophan (L-tryptophan) warfarin, Coumadin, Jantoven diuretics migraine headache medicine (triptans) NSAIDs (nonsteroidal anti-inflammatory drugs): aspirin, ibuprofen, naproxen, celecoxib, diclofenac, meloxicam epilepsy drugs: carbamazepine , phenytoin. Vortioxetine is used to treat major depressive disorder in adults.
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